TAF12 Antibody, HRP conjugated

Datasheet

Code	CSB-PA624102LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TAF12 Polyclonal antibody

Uniprot No.

Q16514

Target Names

TAF12

Alternative Names

TAF12 antibody; TAF12 RNA polymerase II; TATA box binding protein (TBP)-associated factor; 20kDa antibody; TAF12_HUMAN antibody; TAF15 antibody; TAF2J antibody; TAFII 20/TAFII 15 antibody; TAFII-20/TAFII-15 antibody; TAFII20 antibody; TAFII20/TAFII15 antibody; Transcription initiation factor TFIID 20/15 kDa subunits antibody; Transcription initiation factor TFIID subunit 12 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Transcription initiation factor TFIID subunit 12 protein (1-161AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription.

Gene References into Functions

Ectopic expression of the TAF4 histone-fold fragment can efficiently squelch TAF12 in cells PMID: 29316427
We show that two genes, TDP1, a tyrosyl-DNA-phosphdiesterase, and TAF12, an RNA polymerase II TATA-box binding factor, cause CIN when overexpressed in human cells. Using SDL screens in yeast, we identified a set of genes that when deleted specifically kill cells with high levels of Tdp1 PMID: 27551064
TAF12 and NFYC are transcription factors that regulate the epigenome, whereas RAD54L plays a central role in DNA repair PMID: 25965574
ATF7 interacts with TAF12 and contributes to the hypersensitivity of OCL precursors to 1,25-(OH)D in PD. PMID: 23426901
TAF12 hitherto regarded as RNA polymerase II (RNAP II)-specific was found to be also involved in RNAP I transcription. PMID: 17268553

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Subcellular Location

Nucleus.

Protein Families

TAF12 family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 11545

OMIM: 600773

KEGG: hsa:6883

STRING: 9606.ENSP00000263974

UniGene: Hs.530251

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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